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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATF4
All Species:
28.79
Human Site:
S215
Identified Species:
63.33
UniProt:
P18848
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18848
NP_001666.2
351
38590
S215
I
K
E
E
D
T
P
S
D
N
D
S
G
I
C
Chimpanzee
Pan troglodytes
XP_001165876
351
38562
S215
I
K
E
E
D
T
P
S
D
N
D
S
G
I
C
Rhesus Macaque
Macaca mulatta
XP_001099190
351
38511
S215
I
K
E
E
D
T
P
S
D
N
D
S
G
I
C
Dog
Lupus familis
XP_531731
350
38528
S215
I
K
E
E
D
A
P
S
D
N
D
S
G
I
C
Cat
Felis silvestris
Mouse
Mus musculus
Q06507
349
38337
S214
V
K
E
E
D
T
P
S
D
N
D
S
G
I
C
Rat
Rattus norvegicus
Q9ES19
347
38133
S213
V
K
E
E
D
T
P
S
D
S
D
S
G
I
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519185
358
39350
D217
R
E
E
E
A
P
S
D
N
D
S
G
I
C
M
Chicken
Gallus gallus
NP_990211
354
38972
S215
E
K
E
E
E
N
H
S
D
D
S
G
I
C
M
Frog
Xenopus laevis
NP_001083212
336
36859
S211
M
S
P
S
Y
L
E
S
P
Q
Q
S
P
S
V
Zebra Danio
Brachydanio rerio
Q6NW59
339
36586
S217
N
I
S
D
C
S
D
S
D
S
G
I
S
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393709
357
41262
T211
V
P
L
D
Q
I
N
T
D
V
A
H
D
L
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98.2
90.5
N.A.
86
87.1
N.A.
71.2
64.4
54.1
32.7
N.A.
N.A.
24.6
N.A.
N.A.
Protein Similarity:
100
99.1
98.5
93.1
N.A.
90.5
91.1
N.A.
81.5
78.8
66.6
48.4
N.A.
N.A.
39.2
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
13.3
33.3
13.3
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
33.3
46.6
20
40
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
19
55
% C
% Asp:
0
0
0
19
55
0
10
10
82
19
55
0
10
0
0
% D
% Glu:
10
10
73
73
10
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
19
55
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% H
% Ile:
37
10
0
0
0
10
0
0
0
0
0
10
19
55
0
% I
% Lys:
0
64
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
10
0
0
0
0
0
0
0
10
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% M
% Asn:
10
0
0
0
0
10
10
0
10
46
0
0
0
0
0
% N
% Pro:
0
10
10
0
0
10
55
0
10
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
10
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
10
0
10
10
82
0
19
19
64
10
10
10
% S
% Thr:
0
0
0
0
0
46
0
10
0
0
0
0
0
0
0
% T
% Val:
28
0
0
0
0
0
0
0
0
10
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _